- The clade 1b strain was first reported in the Congo.
- The strain is found globally closely due to its high spreading capacity.
- Health experts say clade 1b differs from previous strains.
Federal and provincial health authorities have confirmed the presence of the mpox clade 1b variant in Sindh and southern Punjab, which is reportedly a more transmissible and potentially serious strain. The news reported.
Officials, citing laboratory findings, said genetic sequencing of samples collected from Khairpur was carried out at Dow University of Health Sciences, Karachi, confirming the presence of clade 1b, a sublineage of clade I of the mpox virus.
“Clade 1b is considered more virulent and is associated with sustained human-to-human transmission through close contact,” a Health Ministry official said, adding that the strain was first reported in Congo and is being closely monitored internationally due to its outbreak potential.
According to health officials, Sindh has reported more than two dozen suspected and confirmed mox cases, with Khairpur accounting for the majority of infections. At least nine deaths related to the outbreak have been reported in the province.
Overall, more than two dozen confirmed cases have been documented across the country, and additional suspected infections are being investigated in southern Punjab, particularly in Rahim Yar Khan and adjacent districts, indicating possible local transmission between regions.
Health experts believe the actual number of infections could be higher, citing gaps in surveillance and the need to expand testing in affected areas. Public health experts say clade 1b differs from previously reported strains due to its greater transmissibility and possible greater severity, particularly among vulnerable populations, including children and individuals with weakened immune systems.
Mpox is a viral disease that spreads through close physical contact with infected people, contaminated materials, or respiratory droplets during prolonged interaction. Symptoms usually include fever, rash, and swollen lymph nodes, but in severe cases, complications can lead to death.
Health authorities have recommended early detection, isolation of suspected cases and strict compliance with infection prevention and control measures in healthcare settings to limit further spread.
Authorities said coordination is underway between provincial and federal health authorities to strengthen surveillance, ensure timely diagnosis and manage suspected and confirmed cases in affected areas.
