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The Arizona Cardinals will continue to have Jacoby Brissett playing under center for at least the next four weeks.
Kyler Murray, the team’s franchise quarterback, was placed on injured reserve with a midfoot sprain that he has been battling since Week 5.
Head coach Jonathan Gannon, who watched Brissett lead his Arizona team to its first victory since Week 2 on “Monday Night Football” against the Dallas Cowboys, said it was a “collective decision” for Murray to go on IR. He added that the injury is not season-ending and that he hopes Murray can make a full recovery this year.
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Arizona Cardinals quarterback Kyler Murray (1) warms up before the game against the Dallas Cowboys at AT&T Stadium. (Jerome Miron/Imagn Images)
“I really believe it,” he said via ESPN. “We have a lot to play for, and one day at a time. And where he is now is that he has to dedicate himself to his health and prepare to recover.”
While it’s never a good thing for a franchise quarterback to land on the injured list, the Cardinals can’t complain after seeing what Brissett did against the Cowboys on Monday night. Dallas’ porous defense was exploited by the veteran journeyman, who threw for 261 yards and two touchdowns with a 115.1 passer rating in the 27-17 victory.
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The Cardinals are now 3-5 so far this year, and things could be very different if one of their one-score games during the five-game losing streak they just snapped had gone their way. Unfortunately, that’s the nature of the NFL, but the Cardinals know they have the right man at the helm to get the job done until Murray returns.

Jacoby Brissett of the Arizona Cardinals throws against the Dallas Cowboys during the first quarter of the game at AT&T Stadium on November 3, 2025 in Arlington, Texas. (Sam Hodde/Getty Images)
Looking at the schedule, the Cardinals could get Murray back in Week 14 when they face their NFC West foe, the Los Angeles Rams. Obviously, this wasn’t what Gannon and the rest of the team wanted to see from Murray’s injury, although he acknowledged the fair assessment that the former No. 1 overall pick’s running ability could be prolonging the situation because of the way he plays.
“Obviously, for him, that prevents him from being completely healthy to play, and for him, as a person and player that he is, yes,” Gannon explained. “And you could consider other things, like this injury for other people might not be it, but he’s played some things that other positions, if they have them, they can’t play with because of what they’re asked to do.”
Arizona faces some tough opponents over the next four games, starting with a trip to Seattle to face the NFC West-leading Seahawks on Sunday. The Cardinals then return home for two straight games against the San Francisco 49ers and Jacksonville Jaguars before hitting the road for a showdown with the Tampa Bay Buccaneers before the Rams game on Dec. 7, when Murray could return.

Kyler Murray #1 of the Arizona Cardinals looks on from the sideline before an NFL football game against the Los Angeles Rams at State Farm Stadium on November 26, 2023 in Glendale, Arizona. (Ryan Kang/Getty Images)
It’s a tall order for Brissett to take over and lead the Cardinals now given their 3-5 record. But that’s the nature of being a backup quarterback: When your number is called, you have to deliver.
Brissett did it Monday night and it will be up to him to continue providing that offensive spark over the next month.



