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The Buffalo Bills and the Philadelphia Eagles are at the top of the NFL during the first four weeks of the 2025 season, defeating each team that has been in their schedule so far.
In week 5, both teams can have their biggest tests so far.
The Bills will receive the New England Patriots in a rivalry game of the division that could affect the future planting of playoffs if Josh Allen and Drake Maye have strong seasons. His confrontation will put the exclamation point on an interesting Sunday.
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The Eagles will take their defense tour of the Super Bowl title back to Lincoln Financial Field to face the Denver Broncos. Denver enters the game with a fantastic defense that completely suffocated Jake Browning and the Cincinnati Bengals. Stop Tush’s thrust could be one of the objectives for the Broncos, but the Eagles showed that last week they have some tricks under their sleeves to keep the defenses at the foot.
Four teams have goodbye this week, including the Atlanta Falcons, the Chicago Bears, the Green Bay Packers and the Pittsburgh Steelers. In addition, the Minnesota Vikings will become the first NFL team to play consecutive international games with their confrontation against the Cleveland Browns in London.
Read below to see the rest of the schedule.
Thursday, October 2, 2025
The teammates congratulate the closed wing of the San Francisco 49ers (88) after scoring against the Jacksonville Jaguars during the second half of a NFL football match in Santa Clara, California, on Sunday, September 28, 2025. (AP Photo/Godofredo A. Vásquez)
- San Francisco 49ers @ los angeles rams (8:15 pm et)
Sunday, October 5, 2025
- Minnesota Vikings @ Cleveland Browns (9:30 am et)
- Las Vegas Raiders @ Indianapolis Colts (1 pm et)
- New York Giants @ New Orleans Saints (1 PM ET)
- Dallas cowboys @ new york jets (1 pm et)
- Denver broncos @ philadelphia eagles (1 pm et)
Vikings, the Browns face in London in the first beginning of the rookie seafood Dillon Gabriel
The Buffalo Bills Campo Marshal, Josh Allen (17) fights the New Orleans Saints in the first half of a NFL football match, on Sunday, September 28, 2025, in Orchard Park, New York. (AP Photo/Sue Ogocki)
- Miami Dolphins @ Carolina Panthers (1 PM ET)
- Houston Texans @ Baltimore Ravens (1 PM ET)
- Tennessee titans @ arizona cardinals (4:05 pm et)
- Tampa Bay buccaneers @ seattle sehawks (4:05 pm et)
- Detroit Lions @ Cincinnati Bengals (4:25 PM ET)
- Washington commanders @ los angeles chargers (4:25 pm et)
- New England Patriots @ buffalo bills (8:20 pm et)
Monday, October 6, 2025
The Kansas City Chiefs Campo Marshal, Patrick Mahomes, calls in the Scrimmage line during the first half of a NFL football match against the Baltimore Ravens on Sunday, September 28, 2025 in Kansas City, Missouri. (Photo AP/Charlie Riedel)
- Kansas City chiefs @ jacksonville jaguars (8:15 pm et)
