- One report finds that 78% choose OpenAI models, but many are divided into multiple families and generations.
- Anthropic started to recover in mid-2025, with 75% using Sonnet/Opus 4.5.
- M365 Copilot remains a firm favorite, far outperforming Gemini in Workspace
OpenAI, maker of ChatGPT, remains the most popular model provider chosen by enterprises, according to new data from Global 2000 enterprise CIOs, with nearly four in five (78%) choosing OpenAI models for production.
However, models from rival companies Anthropic and Google are gaining popularity, and Anthropic’s acceptance will increase from mid-2025.
But most importantly, data from venture capitalist giant Andreessen Horowitz (a16z) reveals that specific use cases will play the biggest role in the model decision.
OpenAI’s popularity will soon be challenged by Anthropic
CIOs prefer OpenAI for general chat, knowledge management, and customer support, but Anthropic is gaining popularity for its better performance in software development and data analytics. CIOs noted that Gemini performs well overall, but falls behind in some coding use cases.
And like hybrid and multi-cloud models, companies are moving away from supporting a single vendor, with 81% now using three or more model families in testing or production. This figure has already increased from 68% in less than a year.
As for Anthropic, clearly their newer models are having more success than the previous generation models. Three out of four Anthropic customers had Sonnet 4.5 or Opus 4.5 in production, compared to OpenAI, whose customers still use many older models. Less than half (46%) used GPT-5.2.
Part of this trend could be attributed to the models’ reasoning capabilities, as companies claim faster time to value, less rapid engineering, and greater trust.
a16z also highlighted the proliferation of Microsoft 365 Copilot in the enterprise world, which is much more popular than Google Gemini for Workspace.
Looking ahead, most companies are still measuring the ROI of AI in terms of productivity and cost savings, but employee and customer satisfaction and retention are starting to gain traction. Four out of five of the Global 2000 companies expect to break even or generate a higher return on investment.
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