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Deion Sanders expressed earlier in the week that the Colorado Buffaloes needed to bounce back from a crushing loss to the Utah Utes and move on from it, but Saturday night’s loss increased the pressure on the Pro Football Hall of Famer.
The Arizona Wildcats defeated Colorado, 52-17, marking another disastrous loss for Coach Prime. Colorado trailed 38-7 at halftime and committed five turnovers and 14 penalties throughout the game.
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Colorado head coach Deion Sanders, center, talks with linebacker Shaun Myers, front, as cornerback Preston Hodge looks on in the first half of an NCAA college football game against Arizona, Saturday, Nov. 1, 2025, in Boulder, Colorado. (AP Photo/David Zalubowski)
Sanders did not allow his players to speak to the media after the game. He said it was because the loss fell solely on his shoulders.
“Don’t attack the coordinators. Come to me. Don’t attack the players. Come to me,” he said.
Sanders had no answer for the team’s poor play, but he did dismiss a question about whether his players had retired during the game.
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Colorado head coach Deion Sanders checks the scoreboard in the first half of an NCAA college football game against Arizona, Saturday, Nov. 1, 2025, in Boulder, Colorado. (AP Photo/David Zalubowski)
“I know someone who quits smoking when I see one. I haven’t seen that,” he said.
Sanders added that he had no doubts about his own abilities to get the team back into the win column.
Colorado quarterback Kaidon Salter was benched late in the first half for Ryan Staub. However, Staub was benched later, allowing freshman Ju-Ju Lewis to get some reps. Lewis threw a 59-yard touchdown pass to Omarion Miller, but he ended up leaving the game due to an injury.
The Buffaloes defense allowed Arizona quarterback Noah Fifita to throw four touchdown passes in the game.

Arizona quarterback Noah Fifita, left, passes the ball as Colorado defensive tackle Anquin Barnes Jr. covers in the second half of an NCAA college football game Saturday, Nov. 1, 2025, in Boulder, Colorado. (AP Photo/David Zalubowski)
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Colorado fell to 3-6 on the season. Arizona improved to 5-3.



