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Bookmakers point out that because information is king when it comes to the NFL Draft, it is difficult for them to win the day.
This also means that analysts and fans who have been paying close attention, or who have inside information, could be in a good position when betting on how many players from each major conference will be selected in Round 1.
Let’s take a look at those odds at Draftkings Sportsbook as of April 22.
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2026 NFL Draft
Total Big Ten players selected in the first round
Under 11.5: -165 (bet $10 to win $16.06 total)
Over 11.5: +125 (bet $10 to win $22.50 total)
Total ACC players selected in the first round
Under 6.5: -700 (bet $10 to win $11.43 total)
Over 6.5: +400 (bet $10 to win $50 total)
What to know: Based on the odds, the ACC could only have a handful of players off the board Thursday night. And there’s some analysis to back up those odds, too. In his most recent mock draft, FOX Sports senior college football analyst Joel Klatt has five ACC players in the first round. On their Miami roster are Francis Mauigoa (projected No. 4 pick), Rueben Bain Jr. (No. 12) and Akheem Mesidor (No. 15). Also from the ACC, he projects two Clemson Tigers, TJ Parker and Blake Miller, to come off the board at 22 and 23, respectively.
Total of 12 great players selected in the first round
Under 5.5: -270 (bet $10 to win $13.70 total)
Over 5.5: +190 (bet $10 to win $29 total)
Total SEC players selected in the first round
Under 8.5: -185 (bet $10 to win $15.41 total)
Over 8.5: +140 (bet $10 to win $24 total)
What to know: In the 2025 NFL Draft, 15 SEC players were selected in Round 1. Will the “it just means more” conference continue its first-round reign in 2026? According to FOX Sports NFL analyst Bucky Brooks, bettors may want to keep an eye on the Over. He predicts nine SEC players will hear their names called Thursday. That includes Mansoor Delane (LSU), Monroe Freeling (Georgia), Jermod McCoy (Tennessee), Chase Bisontis (Texas A&M), Kadyn Proctor (Alabama), Keldric Faulk (Auburn), Cashius Howell (Texas A&M), Colton Hood (Tennessee) and KC Concepción (Texas A&M).
